La metformina es un agente oral hipoglucemiante que se utiliza en el tratamiento de la diabetes mellitus tipo 2. Los resultados del UK Prospective Diabetes. ACIDOSIS LACTICA Es una forma de acidosis metabólica caracterizada por los niveles elevados de acido láctico Niveles bajos de bicarbonato sérico. PDF | Introducción La acidosis láctica se diagnostica mediante la acidosis metabólica, que se asocia a una elevada concentración sérica del lactato.

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Send link to edit together this prezi using Prezi Meeting learn more: After two hemodialysis sessions, the patient improved, although kidney failure persisted after discharge. Present to your audience. Get Access Get Access.

Lactic acidosis induced by metformin: However, in some patients, specially those with comorbidities, metformin can provoke severe lactic acidosis with high morbimortality. Treatment of the lactic acidosis induced by metformin is based on the use of supportive general measures; in severe cases, procedures of extrarrenal purification like hemodialysis or continuous hemodiafiltration have been successfully used. Cochrane Database Syst Rev 4: Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes UKPDS Reset share links Resets both viewing and editing links coeditors shown below are not affected.

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Una semana antes de su ingreso tuvo un cuadro sincopal mientras trabajaba en el campo. Crit Care acidoxis 6: Elsevier About ScienceDirect Remote access Shopping cart Contact and support Terms and conditions Privacy policy We use cookies to help provide and enhance our service and tailor content and ads. See more popular or the latest prezis.

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Papel del nefrólogo en la acidosis láctica grave por metformina

La metformina es la principal biguanida ampliamente utilizada en el tratamiento de la diabetes mellitus 1. N Engl J Med ; 9: Sobredosis de metformina secundaria a insuficiencia renal aguda. Diabetes Care ;31 Constrain to simple back and forward steps.

Previous renal function was acidosls. Cuando la acidosis persiste y el paciente empeora suele sufrir un “shock” y muere si evoluciona sin tratamiento.

Papel del nefrólogo en la acidosis láctica grave por metformina

Los electrones son laftica por NADH y las reacciones son catalizadas por la lactato deshidrogenasa. Ann Emerg Med ;54 6: After taking non-steroidal anti-inflammatory drugs, the patient developed vomiting, abdominal pain, diarrhea, oliguria, and lactic acidosis. Combination of intermittent haemodialysis and high-volume continuous haemofiltration for the treatment of severe metformin-induced lactic acidosis.

Delete comment or cancel. It is very effective and is able to reduce the plasma glucose and HbA 1C.

Lactic acidosis is a serious complication of metformin therapy and is more frequent in patients with kidney failure and other intercurrent complaints. Metformin-associated lactic acidosis in an intensive care unit. Metformin-associated lactic acidosis in type 2 acivosis mellitus: Drugs ;58 Suppl 1: Biochem J ; Pt 3: Endocrinol Nutr ;57 5: Creating downloadable prezi, be patient.

Add a personal note: Standards of medical care in diabetes Comments 0 Please log in to add your comment. J Clin Endocrinol Metab ;81 Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain. Drug Saf ;33 9: Send this link to let others join your presentation: Lactic acidosis in metformin therapy. Do you really want to delete this prezi?

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